New 4 year BBSRC PhD available in the lab!

A joint PhD opportunity, fully funded by the BBSRC for EU applicants, will soon become available between the Lloyd-Evans and Berry laboratories at the School of Biosciences, Cardiff University.

Project title – “Molecular mechanisms of action for the Toxin_10 insecticidal proteins”

Project description (brief) – Insecticidal toxins are crucial molecules for pest control. This project combines molecular and protein characterisation of some of the members of this family. We will further characterise their molecular interactions with plasma membrane receptors and lipids including their subsequent endocytosis into the cell and the mechanisms by which they induce cell death. The goal of this project is to elucidate the mechanisms by which these toxins function to improve our understanding of their insecticidal modes of action and to develop new tools for mammalian cell biology.

This PhD will be advertised on FindaPhD (shortly) and the SWBio website (

Deadline for applications is December 4th 2017.

For further information or any queries regarding this PhD please contact Emyr.

Image: Predicted structure of a Toxin_10 family member courtesy of Dr. Colin Berry

MRC funded PhD studentship opportunity available in the ELE lab

We’re pleased to announce that our project on the role of nanoparticle toxicity in neuronal health and Alzheimer’s disease has been selected for competitive funding. These PhD’s are fully funded by the MRC as part of the GW4 consortium and are open to students from European countries who have relevant biological sciences undergraduate degrees. We are looking for highly motivated, high quality students to apply for this PhD, the best candidate will then be put forward for interview with a select number of the best students being picked for a number of PhD’s across the consortium.

The project itself is predominantly focused on identifying the impact of metallic nanoparticles on the brain, with a particular focus on the recent evidence connecting iron nanoparticles with Alzheimer disease. As these nanoparticles normally accumulate within lysosomes, we will utilise our particular expertise in this area to determine the impact of the particles on lysosomal function in the brain and will attempt to determine if lysosomal dysfunction is an underlying cause of the association between iron nanoparticles and Alzheimer’s. We will also be investigating the use of novel nanoparticles for utilisation in lysosomal purification technology.

Anyone who is interested in applying is encouraged to initially contact Dr. Lloyd-Evans by e-mail with a CV. Quality of CV, application material and an informal interview are essential components in deciding who will ultimately be put forward for the eventual PhD interview.

More information can be found at:

And details on how to apply can be found here:

Deadline for applications is 9am (morning!) on June 8th, interviews will take place on Friday, June 30th.